Hard capsules are divided into gelatin capsules and vegetable capsules according to the different raw materials. Gelatin capsules are currently the most popular two-section capsules in the world. The main ingredient is high-quality medicinal gelatin. The vegetable capsules are made of vegetable cellulose or water-soluble polysaccharides. The hollow capsule made of raw materials retains all the advantages of the standard hollow capsule. Both have certain differences in raw materials, storage conditions, production processes and characteristics.
capsules are usually divided into hard capsules and soft capsules. Hard capsules, also known as hollow capsules, are composed of two parts of the cap body; soft capsules are processed into products with film-forming materials and contents at the same time. Hard capsules are divided into gelatin capsules and vegetable capsules according to the different raw materials. Gelatin capsules are currently the most popular two-section capsules in the world. The capsule is composed of two precision-machined capsule shells. The size of the capsules is varied, and the capsules can also be colored and printed to present a unique customized appearance. Plant capsules are hollow capsules made of plant cellulose or water-soluble polysaccharides as raw materials. It retains all the advantages of standard hollow capsules: convenient to take, effective in concealing taste and smell, and the contents are transparent and visible.
What are the differences between gelatin capsules and vegetable capsules
1. The raw materials of gelatin capsules and vegetable capsules are different
The main component of the gelatin capsule is high-quality medicinal gelatin. The collagen in the skin, tendons and bones of the gelatin-derived animal is a protein that is partially hydrolyzed from the collagen in the animal connective tissue or epidermal tissue; the main component of the vegetable capsule is medicinal hydroxypropyl. HPMC is 2-hydroxypropyl methyl cellulose. Cellulose is the most abundant natural polymer in nature. HPMC is usually made from short cotton linter or wood pulp through etherification.
2, the storage conditions of gelatin capsules and vegetable capsules are different
In terms of storage conditions, after a lot of tests, it is almost not brittle under low humidity conditions, and the properties of the capsule shell are still stable under high temperature and humidity, and the various indexes of plant capsules under extreme storage conditions are not affected. Gelatin capsules are easy to adhere to the capsules under high humidity conditions, harden or become brittle under low humidity conditions, and are highly dependent on the temperature, humidity and packaging materials of the storage environment.
3, the production process of gelatin capsules and vegetable capsules is different
The plant hydroxypropyl methylcellulose is made into the capsule shell, and it still possesses the natural concept. The main component of hollow capsules is protein, so it is easy to breed bacteria and microorganisms. Preservatives need to be added during the production process, and the finished product needs to be sterilized with ethylene oxide before packaging to ensure the microbial control indicators of the capsules. The plant capsule production process does not need to add any preservatives, and does not need to be sterilized, which fundamentally solves the problem of preservative residues.
4, the characteristics of gelatin capsules and vegetable capsules are different
Compared with traditional hollow gelatin capsules, vegetable capsules have the advantages of wide adaptability, no risk of cross-linking reaction, and high stability. The drug release rate is relatively stable, and individual differences are small. After disintegration in the human body, it is not absorbed and can be excreted. Excreted from the body.
Post time: Jun-16-2021